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備註請放最後面 違者新聞文章刪除

1.媒體來源:

外媒    BGR

2.記者署名:

By Joshua Hawkins

3.完整新聞標題:

Scientists might actually create hypoallergenic cats

學界展開針對貓咪的基因改造計劃以降低過敏性

4.完整新聞內文:

Scientists might actually create hypoallergenic cats

學界展開針對貓咪的基因改造計劃以降低過敏性

Home Science News

By Joshua Hawkins
April 1st, 2022 at 4:17 PM
cat

People with cat allergies may be able to have a cat sometime in the future
thanks to gene-editing technology. Of course, the creation of truly
hypoallergenic cats is far off. But, scientists believe they could use
CRISPR, a gene-editing tool, to remove the gene responsible for creating the
protein that causes cat allergies.



How bad are cat allergies today?

今天貓過敏有多嚴重？

Cats are everywhere, plus they make great pets. That’s why dealing with cat
allergies has become such a huge problem for many people. A study from 2018
says that between 10 to 20 percent of the world’s population deals with cat
allergies of some kind. One of the big culprits of these allergies is a
protein called Fel d 1.

貓無處不在，而且它們是很棒的寵物。這就是為什麼處理貓過敏已成為許多人的大問題。
2018 年的一項研究表明，世界上有 10% 到 20% 的人口患有某種貓過敏症。這些過敏的
罪魁禍首之一是一種叫做 Fel d 1 的蛋白質。

When cats produce this protein, it ends up in their saliva and tears. It is
then transferred, obviously, to their fur through constant cleaning. From
there, it’s transferred to our homes as they shed their hair and it blends
with the dust around the house. It’s a constant cycle and one that has left
many people dealing with terrible allergies over the years.



Sure, there are some hypoallergenic cat breeds out there. However, they all
still create this protein, just some in lesser quantities. So, while they may
not produce Fel d 1 levels that are dangerous, they can still lead to an
allergic response over time.



Making a truly hypoallergenic cat

做一隻真正的低度過敏貓

It’s this widespread allergy issue that has led scientists at the
Virginia-based biotech company InBio to investigate making a truly
hypoallergenic cat. The company published a study on the matter earlier this
week in The CRISPR Journal, detailing how they think they can accomplish this
goal.



Evolutionary Biology and Gene Editing of Cat Allergen, Fel d 1

https://www.liebertpub.com/doi/10.1089/crispr.2021.0101

The scientists say they analyzed the DNA of 50 domestic cats and found
regions along two genes that they believe are primarily responsible for
producing Fel d 1. They also found that these regions may be suitable for
editing using CRISPR’s gene-editing technology. The researchers then
compared their domestic findings with those of eight wilder cat species.

科學家們說，他們分析了 50 隻家貓的 DNA，並發現了他們認為主要負責產生 Fel d 1
的兩組基因的區域。他們還發現這些區域可能適合使用 CRISPR 的基因編輯技術進行編輯
。然後，研究人員將他們的國內發現與八種野生貓科動物的發現進行了比較。

Here, they found a large discrepancy between the levels of Fed d 1 in the
different groups. This, they say, could indicate that Fel d 1 is not
essential to cat biology. As such, they believe they can remove it without
posing a health risk to the cats involved. They tested this theory by editing
cat cells in the lab using CRISPR. The results produced no off-target changes
in the areas where they thought it might occur.



Of course, there’s still a long way to go before these scientists start
breeding hypoallergenic cats. Still, it’s interesting to look at how tools
like CRISPR allow us to change things at a genetic level. We’ve also
recently seen gene-editing take a fascinating approach in genetically
modified mosquitos. Allowing scientists to create a subspecies capable of
helping cull the population of disease-carrying insects.



5.完整新聞連結 (或短網址)需放媒體原始連結，不可用轉載媒體連結:

https://bgr.com/science/scientists-might-actually-create-hypoallergenic-cats/

6.備註:




                                這安全嗎？










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作為密義源起供養；然而聚歛於上的是冥界的深冤與大樂奔瀉的淨慈，行者於閉關修持
之時若生起退失動搖之心，則神識旋即離散且肉身消殞；即便如此還是願意受灌頂嗎？
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